Pueraria Mirifica
Scientific Name(s) : Pueraria Mirifica
Family : Leguminosae
Common Name(s) : Kwao Krua Kao, White Kwao Krua (Thailand)
Aging Problems ? How Pueraria mirifica can solve it.
Most women are very concerned about aging, particularly the effects brought about by the aging process.
For the average women, menstruation cycles end at 48-50 years of age when the reproductive system stops
or slows down functioning. The body experiences dramatic changes due to lower estrogen levels: the body's
systems and its functions begin to decelerate and the immune system weakens, accordingly menopausal
women will usually experience both psychological and physiological changes. Psychological changes range
from anxiety, tension and nervousness to chronic depression, whereas the physiological changes include hot
flushes, fatigue and insomnia to more severe conditions as bone loss, balding and degeneration of the
reproductive area.
Consequently, women at the age of 45-50 and post-menopausal women need something to replace the loss
of natural estrogen. Hormone replacement therapy (HRT) has been extensively used to alleviate both the
psychological and physiological changes. However, this estrogen substitute can be quite expensive and
must be conducted under a physician's close supervision. An effective alternative approach would be to
delay those aging problems by using natural phytoestrogens present in Pueraria mirifica as a dietary
supplement.
Health benefit of phytoestrogens is at least two folds. Firstly, as stated earlier, Pueraria mirifica contains
various kinds of phytoestrogens, e.g., miroestrol, deoxymiroestrol, genistein, daidzein, daidzin, genistin,
coumestrol, etc. These phytoestrogens can bind to the estrogen receptors like estrogen does with different
degrees of affinity giving different estrogenic potency. When Pueraria is taken, its
phytoestrogens would go around the body through blood circulation and bind estrogen
receptors present in various organs. This would help restore normal function of the body once
slow down due to the aging process. Hence, phytoestrogens from Pueraria mirifica can correct
estrogen insufficiency in the body and relieve the post-menopausal symptoms.
Secondly, there is evidence to support that phytoestrogen consumption contributes to lower
risks of cardiovascular disease and that phytoestrogens may even prevent cardiovascular-
related diseases. In a study, it was proven that phytoestrogens in soybeans could decrease the level of LDL
cholesterol and increase the level of HDL cholesterol in the blood; therefore, reducing the risk of
cardiovascular diseases. Moreover, it was reported that subjects who consumed soy at least three times daily
had a decrease in the levels of total cholesterol, LDL cholesterol and triglyceride. It is quite likely that
phytoestrogens from Pueraria mirifica will work just the same or even better than isoflavones since, in the
previously mentioned toxicity study in rats, a very significant reduction of blood cholesterol levels in all
groups of Pueraria mirifica-treated rats was also observed.
Preliminary data from a clinical trial conducted in Thailand to study the beneficial effect of Pueraria
mirifica supplement have recently been obtained. Eight female subjects who were having menopausal
symptoms received Pueraria mirifica in the form of capsule once daily at the dose of 200 mg for 4 months
followed by the dose of 100 mg, for 8 months. Improvement of menopausal symptoms was observed in 5
out of 8 subjects throughout the study period. Physical examinations and biochemical studies revealed that
all subjects were healthy. The dietary supplement dose of Pueraria mirifica recommended by the physician
for its estrogenic effect in this case is 100 mg per day.
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